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I had used two other matchmaking services caasual — both of them used high pressured sales techniques and arranged blind valelyford Free casual dating in valleyford wa 99036 me. These claims were not valleyforv by numerous publications dating from the sshowing that such lubricants caused significant harm to sperm in vitro equivalent to contraceptive gels ; as well as in vivo Figure 1 [ 18 - 25 ]. Effect of intravaginal Patient Lubricant Surgilube on sperm penetration and motility in cervical mucus during postcoital examination adapted from Miller, et al. These clearances established the concept of lubricant products designed specifically to not harm sperm, oocytes, fertilization or embryos when conception was desired; as well as created a pathway for Fertility Lubricant testing and review.
A key aspect of the PEB Lubricants is that they must have physical properties in a narrow range e. Specifically, these products are in the range of pH neutrality e. Additional unique testing for Fertility Lubricants includes assessing the impact of the product on: Finally, endotoxin screening in the PEB Lubricants at production and over time, are required due to the deleterious impact of even very low levels of endotoxin on gamete and embryo function [ 2642 - 47 ]. These products may impact vulnerable fertility patients where inflated, false claims or harmful product properties can be particularly deleterious. Health care providers offer a first line of defense in protecting patients through notification of local FDA authorities when illegal products are identified.
The regulatory status of any lubricant can quickly be assessed utilizing the FDA k searchable database at https: However, natural products can be contaminated with high endotoxins, heavy metals and even bacteria, all of which can profoundly impair gamete and embryo function [ 264849 ].
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